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Preparation, Resolution and Optical Stability of 3,4-Dehydroproline and 3,4-Dehydroprolinamide

✍ Scribed by Robertson, Alexander V.; Witkop, Bernhard.


Book ID
120809038
Publisher
American Chemical Society
Year
1962
Tongue
English
Weight
663 KB
Volume
84
Category
Article
ISSN
0002-7863

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mixture was poured into ice-water(l00 ml) and extracted with CHC13(100 ml x 3). The extract was washed with H20, dried over MgS04 and evaporated to give Z-methylpropyl phenyl ketone(5d) as an oil(l6.20 g, 94%). 'H-NMR: 8.00(2H,dd,J=8.5 and 1.5Hz1, 7.60-7.23 (3H,m), 2.84(2H,d, J=6.8Hz), 2.40-2.08(lH,