𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Preparation of tris-based dendrimer-grafted core-shell type resin for solid-phase peptide synthesis

✍ Scribed by Jin Ku Cho; Do-Won Kim; Jayoung Namgung; Yoon-Sik Lee

Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
90 KB
Volume
42
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

A novel symmetrical dendrimer monomer was synthesized from tris(hydroxymethyl)aminomethane (Tris) and repeatedly coupled to a core-shell type resin. The loading capacity of amino groups was increased up to 4.0 mmol g -1 resin by the dendrimerization process. The high loading dendrimer-grafted resin produced was successfully applied to solid-phase peptide synthesis (SPPS).

📜 SIMILAR VOLUMES

Preparation of a core–shell type MBHA re
Preparation of a core–shell type MBHA resin and its application for solid-phase peptide synthesis
✍ Jeong-Hyun Choi; Tae-Kyung Lee; Jang-Woong Byun; Yoon-Sik Lee 📂 Article 📅 2009 🏛 Elsevier Science 🌐 French ⚖ 349 KB

## a-Amidoalkylation Partial hydrolysis Solid-phase peptide synthesis a b s t r a c t MBHA (4-methylbenzhydrylamine) resin has been extensively used as a solid support for the synthesis of peptide amides. Herein, we prepared the core-shell-type MBHA resin by benzotriazole-catalyzed amidoalkylation