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Preparation of surfactant-stabilized gold nanoparticle–peptide nucleic acid conjugates

✍ Scribed by Janice Duy; Laurie B. Connell; Wolfgang Eck; Scott D. Collins; Rosemary L. Smith

Book ID
106477899
Publisher
Springer Netherlands
Year
2010
Tongue
English
Weight
336 KB
Volume
12
Category
Article
ISSN
1388-0764

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## Abstract Peptide nucleic acids (PNA) and PNA–DNA chimeras carrying thiol groups were used for surface functionalization of Au nanoparticles. Conjugation of PNA to citrate‐stabilized Au nanoparticles destabilized the nanoparticles causing them to precipitate. Addition of a tail of glutamic acid t