Preparation of Some N-Substituted Hexahydro-4 H -azepin-4-ones
✍ Scribed by Laronze, J-Y.; Dridi, S.; Sapi, J.
- Book ID
- 121003113
- Publisher
- Taylor and Francis Group
- Year
- 1991
- Tongue
- English
- Weight
- 153 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0039-7911
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## Abstract A ^1^H and ^13^C NMR conformational study of four __cis__‐fused __N__‐substituted hexahydrocyclopent[__e__][1,3]oxazin‐4‐ones and four __cis__‐fused hexahydro‐2__H__‐1,3‐benzoxazin‐4‐ones at various temperatures revealed several dynamic conformational processes to be in effect. These in
## Abstract The synthesis of 5,6,7,8‐tetrahydro‐4__H__‐oxazolo[4,5‐__c__]azepin‐4‐ones **5a,b** and 1,3‐benzoxazol‐4‐amines **4a,b** are described starting from 4,5,6,7‐tetrahydro‐1,3‐benzoxazol‐4‐ones. Thionation of **5a,b** followed by alkylation with ethyl bromoacetate led to the corresponding _