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Preparation of radioiodinated ritodrine as a potential agent for lung imaging

✍ Scribed by Rashed, H. M.; Ibrahim, I. T.; Motaleb, M. A.; El-Bary, A. Abd

Book ID: 125364933
Publisher: Springer
Year: 2014
Tongue: English
Weight: 445 KB
Volume: 300
Category: Article
ISSN: 1588-2780
DOI: 10.1007/s10967-014-3077-2

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## Abstract We report the synthesis and evaluation of 1′‐(4‐[^125^I]iodobenzyl)‐3H‐spiro[isobenzofuran‐1,4′‐piperidine] ([^125^I]Spiro‐I) as a potential SPECT tracer for imaging of σ~1~ receptors. [^125^I]Spiro‐I was prepared in 55–65% isolated radiochemical yield, with radiochemical purity of >99%