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A radioiodinated quinoline DNA complex as a potential melanoma imaging agent

✍ Scribed by Ned D. Heindel; Jacqueline G. Emrich; H.Donald Burns; Robert Dannals; Richard Schneider


Book ID
116083892
Publisher
Elsevier Science
Year
1984
Weight
276 KB
Volume
11
Category
Article
ISSN
0047-0740

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## Abstract We report the synthesis and evaluation of 1′‐(4‐[^125^I]iodobenzyl)‐3H‐spiro[isobenzofuran‐1,4′‐piperidine] ([^125^I]Spiro‐I) as a potential SPECT tracer for imaging of Οƒ~1~ receptors. [^125^I]Spiro‐I was prepared in 55–65% isolated radiochemical yield, with radiochemical purity of >99%