Preparation of porous scaffold from hydroxyapatite powders

✍ Scribed by S.K. Swain; S. Bhattacharyya; D. Sarkar

• Publisher: Elsevier Science
• Year: 2011
• Tongue: English
• Weight: 893 KB
• Volume: 31
• Category: Article
• ISSN: 0928-4931
• DOI: 10.1016/j.msec.2010.11.014

✦ Synopsis

Hydroxyapatite (HA) powder was prepared by wet chemical method. The hydroxyapatite phase was stable up to 1250 °C without decomposition to beta-tricalcium phosphate. Interconnected porous hydroxyapatite scaffold resembling trabecular bone structure was developed from polymeric replica sponge method. The prepared scaffold has 60 vol.% porosity having a major fraction of ~50-125 μm pore diameter. The pore content, pore morphology, pore interconnectivity of scaffold and their compressive strength were dependent on the solid loading and binder content. In-vitro bioactivity and bioresorbability confirmed the feasibility of the developed scaffolds.