Preparation of Poly and Diversely Substituted N-Alkylated and Free-NH Isoindolin-1-ones.
β Scribed by Axel Couture; Eric Deniau; Marc Lamblin; Magali Lorion; Pierre Grandclaudon
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 29 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
## Abstract Lithiation of ureas (I) and (VI) followed by quenching with various electrophiles, such as aldehydes (II), ketones (IV) and alkyl halides (VII) affords the corresponding 3βsubstituted isoindolinβ1βones (III), (V), and (VIII), respectively, in good yields.
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