Preparation of optically pure L-2-hydroxyaldehydes with yeast transketolase
โ Scribed by Franz Effenberger; Volker Null; Thomas Ziegler
- Book ID
- 104215778
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- French
- Weight
- 288 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
Abstr+z LZ-Hydroxyddehydes J--3 with a great variety of substituents in 3-pcsition are qbtained in good chemical and excellent &ii yielda by kinetic resolution in the tmn&etolase-catdyxed reaction of racemic 2.hy4roxyakkhydc-r with lithium hydrexypymvate 4 where only the enamiomer (Rj.3 resets to Sdeexy-D-xyluleses 5.
๐ SIMILAR VOLUMES
Asymmetric reduction of B-ketothioester derivatives with baker's yeast produced the cou'responding optically pure 3S-hydroxythioesters, whic.4 are useful chiral buiZdiz;a blocks in organic synthesis. The util:ity of the present method #eoseLective synthesis of sex attractant !,f pine saw-f?+, 12~,3~