✦ LIBER ✦
Stereocontrol by introduction of a sulfur functional group in the asymmetric reduction of β-ketoesters with baker's yeast; preparation of optically pure 3s-hydroxydithioesters as a new chiral synthon of natural product synthesis
✍ Scribed by Toshiyuki Itoh; Yoshihiro Yonekawa; Toshio Sato; Tamotsu Fujisawa
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- French
- Weight
- 335 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Asymmetric reduction of B-ketothioester derivatives with baker's yeast produced the cou'responding optically pure 3S-hydroxythioesters, whic.4 are useful chiral buiZdiz;a blocks in organic synthesis. The util:ity of the present method #eoseLective synthesis of sex attractant !,f pine saw-f?+, 12~,3~,7~1-3,7-dimet~~Z~?entadec-2-~i: acetate from the SS-hydroxy esters.