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Preparation of new nitrogen-bridged heterocycles. Synthesis and some reactions of 2,3-dihydroindolizin-2-one derivatives

โœ Scribed by Kakehi, Akikazu; Ito, Suketaka; Watanabe, Kozo; Kitagawa, Masahiko; Takeuchi, Sadafumi; Hashimoto, Toshio


Book ID
120436628
Publisher
American Chemical Society
Year
1980
Tongue
English
Weight
695 KB
Volume
45
Category
Article
ISSN
0022-3263

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Indole-2,3-dione ivas treated with malonic acid in a mixture of-ethanol/p?v-idine to afford I - [3-(2-oxoindoliii?.lideiiej]acetic acid (31, ivhich was theta reacted with thionFl chloride to give the corresponding acid chloride (4). The acid chloride 4 reacted with arenes in the presence of AlC1, to