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Preparation of dibarbiturates of oxindole by condensation of isatin and barbituric acid derivatives

✍ Scribed by Branko S Jursic; Edwin D Stevens

Book ID: 104251512
Publisher: Elsevier Science
Year: 2002
Tongue: French
Weight: 127 KB
Volume: 43
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)01107-3

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✦ Synopsis

A very efficient, simple, and high yield procedure for the isatin condensation with barbituric acid derivatives was described. The condensation reaction is very selective, which is corroborated by following the reaction by NMR, and the structure of the product was confirmed by X-ray structural analysis.

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