## Abstract The synthesis of d, l, ‐12‐bromocamptothecin (**2d**) from camptothecin (**1**) is described. Reduction of the bromo derivative **2d** with tritium gas in the presence of palladium on carbon afforded d, l‐camptothecin 12‐^3^H having a specific activity of 29 Ci/mmol. A simpler labelling
Preparation of deuterium and tritium labelled norethynodrel, norethindrone, and 6-methyleneandrostenedione
✍ Scribed by Herbert L. Holland; Frances M. Brown; Liat Tan
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- French
- Weight
- 192 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0022-2135
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