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Preparation of carbon-11 labelled acetate and palmitic acid for the study of myocardial metabolism by emission-computerised axial tomography

✍ Scribed by V. W. Pike; M. N. Eakins; R. M. Allan; A. P. Selwyn


Book ID
112765381
Publisher
Springer
Year
1981
Tongue
English
Weight
337 KB
Volume
64
Category
Article
ISSN
1588-2780

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1-11C-acetoacetic acid was synthesized by carboxylation of the acetone carbanion. Purification was carried out using HPLC. The product was obtained with a radiochemical yield of up to 58%, corrected for decay, in a total preparation time of 30 min. The distribution of 1-11C-acetoacetic acid after in