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Preparation of bipyridyl derivatives via α-lithiation of pyridyl phenyl sulfoxides, substitution with electrophiles and cross-coupling reactions with Grignard reagents

✍ Scribed by Naomichi Furukawa; Tadao Shibutani; Hisashi Fujihara


Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
226 KB
Volume
30
Category
Article
ISSN
0040-4039

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Preparation of pyridyl grignard reagents
✍ Naomichi Furukawa; Tadao Shibutani; Hisashi Fujihara 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 240 KB

Pyridyl Grignard reagents were prepared from the corresponding iodopyridine and EtMgBr. New cross coupling reactions of the Grignard reagents with azaheterocycles took place on the sulfinyl sulfur atom to afford biazaheteroaryls.