𝔖 Bobbio Scriptorium
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Preparation of Bioconjugates through an Ugi Reaction

✍ Scribed by Thomas Ziegler; Sonja Gerling; Martin Lang

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
110 KB
Volume
39
Category
Article
ISSN
0044-8249

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πŸ“œ SIMILAR VOLUMES

An Ugi Reaction in the Total Synthesis o
An Ugi Reaction in the Total Synthesis of (βˆ’)-Dysibetaine
✍ Jerry Isaacson; Yoshihisa Kobayashi πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 295 KB πŸ‘ 2 views

## Abstract **(βˆ’)‐Dysibetaine has been synthesized** in 11 steps from readily available L‐malic acid (see scheme). The key step is a unique Ugi 4‐center‐3‐component cyclization reaction, where an ester group acts as the carboxylic acid component. The use of 1,1,1,3,3,3‐hexamethyldisilazane as an am