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Preparation of .beta.,.beta.-dialkyl analogs of cysteine suitable for peptide synthesis

โœ Scribed by Stanfield, C. Freeman; Cody, Wayne L.; Hruby, Victor J.


Book ID
126294456
Publisher
American Chemical Society
Year
1986
Tongue
English
Weight
567 KB
Volume
51
Category
Article
ISSN
0022-3263

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This paper describes a novel solid phase peptide synthesis method for the systematic C-terminal modification of cysteine-containing peptides. In this method, cysteine is linked to chloromethylated polystyrene resin by its thiol functionality, followed by protection of the N-terminus and derivatizati