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Preparation of a Diverse Purine-Scaffold Library via One-Step Palladium Catalyzed Cross-Coupling

✍ Scribed by Taldone, Tony; Zatorska, Danuta; J. Patel, Hardik; Sun, Weilin; R. Patel, Maulik; Chiosis, Gabriela


Book ID
120454509
Publisher
Japan Institute of Heterocyclic Chemistry
Year
2013
Tongue
English
Weight
895 KB
Volume
87
Category
Article
ISSN
0385-5414

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ChemInform Abstract: Preparation of Benz
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## Abstract A new and efficient method for the synthesis of benzylphosphonate and benzylphosphonothioate diesters (including nucleosides), involves a palladium(0)‐catalyzed cross‐coupling between benzyl halides and H‐phosphonate or H‐phosphonothioate diesters using Pd~2~(dba)~3~(CHCl~3~) as a palla