## Abstract Folic acid plays a key role in nucleic acid biosynthesis, essential for normal cell proliferation and function. Localized folate deficiencies may be related to changes in cytology associated with cancer development; analogs of folic acid, such as methotrexate, are potent chemotherapeuti
Preparation of 3–5 dipropionilamino 2, 4, 6, triiodo benzoic acid I-131
✍ Scribed by A. E. A. Mitta; L. L. Camin; H. E. Huala
- Publisher
- John Wiley and Sons
- Year
- 1967
- Tongue
- French
- Weight
- 248 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
A method is discussed for the labelling of Diprocon by interchange between 131I and inactive Diprocon, obtaining a radiochemical yield over
95
% in only jive minutes.
The effect of p H , temperature and molar relation between the reactants on the radiochemical yield is determined as well as the maximum sterilization time and the optimal storage conditions for the labelled molecule.
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