PREPARATION OF 2(2-HYDROXYMETHYL-6-METHYL)PHENYLETHANOL
β Scribed by Tombari, D. G.; Moglioni, A. G.; Moltrasio Iglesias, G. Y.
- Book ID
- 120521318
- Publisher
- Taylor and Francis Group
- Year
- 1995
- Tongue
- English
- Weight
- 238 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0030-4948
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π SIMILAR VOLUMES
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The preparation of 2-methyl-3-(2-hydroxymethyl)phenyl-4(3H)-quinazalone (Ib), a metabolite of methaqualone [2methyl-3-0-tolyl-4(3H)-quinazalone] (Ia ), is described. Bromination of Ia is accomplished with Nbromosuccinimide in refluxing carbon tetrachloride. Solvolysis of this bromide (If) in buffere