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Preparation of 2-aryl and 2-aryloxymethyl imidazo[1,2-a]pyridines and related compounds

✍ Scribed by Richard J. Sundberg; D. J. Dahlhausen; G. Manikumar; B. Mavunkel; Atanu Biswas; V. Srinivasan; Fred King Jr.; Philip Waid

Book ID: 112128808
Publisher: Journal of Heterocyclic Chemistry
Year: 1988
Tongue: English
Weight: 549 KB
Volume: 25
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570250119

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The synthesis of imidazo [1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives by condensation between an a-bromoketone bound to solid support and various 2-aminopyridine or 2-aminopyrimidine derivatives was described. Either an acid labile linker or a base labile linker was used in this study.