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Preparation of 2-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamides from polylithiated C(α),N-phenylhydrazones and methyl 2-(aminosulfonyl)benzoate

✍ Scribed by Michelle A. Meierhoefer; S. Patrick Dunn; Laela M. Hajiaghamohseni; Matthew J. Walters; Mildred C. Embree; Sally P. Grant; Jennifer R. Downs; Jessica D. Townsend; Clyde R. Metz; Charles F. Beam; William T. Pennington; Donald G. VanDerveer; N. Dwight Camper

Publisher
Journal of Heterocyclic Chemistry
Year
2005
Tongue
English
Weight
92 KB
Volume
42
Category
Article
ISSN
0022-152X

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✦ Synopsis

Select C(α),N-phenylhydrazones were dilithiated in excess lithium diisopropylamide followed by condensation with methyl 2-(aminosulfonyl)benzoate and acid cyclization to afford new pyrazol-benzenesulfonamides, 2-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamides.

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