Preparation of [124I]IBA-annexin-V as a potential pet probe for apoptosis
โ Scribed by M. Glaser; D. R. Collingridge; E. Aboagye; L. Bouchier-Hayes; D. J. Brown; O. C. Hutchinson; S. Martin; P. Price; S. K. Luthra; F. Brady
- Book ID
- 112132560
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- French
- Weight
- 193 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0022-2135
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## Abstract This study describes the radioiodination of an antibody specific to the vascular endothelial growth factor (VEGF), VG76e, with [^124^I]iodine to obtain a novel PET tracer for measurement of angiogenesis. __In vitro__ binding assays showed a significantly higher immunoreactive fraction w
## Abstract Condensation of phenylazoโฮฒโketoamide **4** with oxymorphone **5** afforded an __m__โiodophenylpyrrolomorphinan (__m__โIPPM) **6** mediated by elemental zinc in acetic acid/sodium acetate buffer. __m__โIPPM **6** is a novel opioid receptor agonist (__K__~i~ = 4.53 nM for DOP) with high