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Preparation and radiosynthesis of [18F]FE@CFN (2-[18F]fluoroethyl 4-[N-(1-oxopropyl)-N-phenylamino]-1-(2-phenylethyl)-4-piperidinecarboxylate): a potential μ-opioid receptor imaging agent

✍ Scribed by Wadsak, Wolfgang; Key Mien, Leonhard; Ettlinger, Dagmar E.; Feitscher, Sylvia; Lanzenberger, Rupert; Marton, Janos; Dudczak, Robert; Kletter, Kurt; Mitterhauser, Markus

Book ID
118161999
Publisher
Oldenbourg Wissenschaftsverlag
Year
2007
Tongue
English
Weight
160 KB
Volume
95
Category
Article
ISSN
0033-8230

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Radiosynthesis and in vivo study of [18F
Radiosynthesis and in vivo study of [18F]1-(2-fluoroethyl)-4-[(4-cyanophenoxy)methyl]piperidine: a promising new sigma-1 receptor ligand
✍ Jun Zhao; Raymond Chang; Patty Carambot; Rikki N. Waterhouse 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 124 KB

## Abstract The novel sigma‐1 receptor PET radiotracer [^18^F]1‐(2‐fluoroethyl)‐4‐[(4‐cyanophenoxy)methyl]piperidine ([^18^F]WLS1.002, [^18^F]‐2) was synthesized (__n__=6) by heating the corresponding __N__‐ethylmesylate precursor in an anhydrous acetonitrile solution containing [^18^F]fluoride, Kr