✦ LIBER ✦

Synthesis and in vivo evaluation of [18F]N-(2-benzofuranylmethyl)-N′-[4-(2-fluoroethoxy)benzyl]piperazine, a novel σ1 receptor PET imaging agent

✍ Scribed by Iman A. Moussa; Samuel D. Banister; Nicolas Giboureau; Steven R. Meikle; Michael Kassiou

Book ID: 113496171
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 479 KB
Volume: 21
Category: Article
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2011.09.028

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis and preliminary in vivo evalua

Synthesis and preliminary in vivo evaluation of 4-[18F]fluoro-N-{2-[4-(6-trifluoromethylpyridin-2-yl)piperazin-1-yl]ethyl}benzamide, a potential PET radioligand for the 5-HT1A receptor

✍ M. Vandecapelle; F. Dumont; F. De Vos; K. Strijckmans; D. Leysen; K. Audenaert; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 138 KB 👁 1 views

## Abstract 4‐Fluoro‐__N__‐{2‐[4‐(6‐trifluoromethylpyridin‐2‐yl)piperazin‐1‐yl]ethyl}benzamide is a full 5‐HT~1A~ agonist with high affinity (__pK__~__i__~=9.3), selectivity and a __c__ log __P__ of 3.045. The corresponding PET radioligand 4‐[^18^F]fluoro‐__N__‐{2‐[4‐(6‐trifluoromethylpyridin‐2‐yl)

Design, Synthesis, and Preliminary in Vi

Design, Synthesis, and Preliminary in Vitro and in Vivo Evaluation of N -(2-diethylaminoethyl)-4-[ 18 F]fluorobenzamide ([ 18 F]-DAFBA): A Novel Potential PET Probe to Image Melanoma Tumors

✍ Garg, Sudha; Kothari, Kanchan; Thopate, Shankar R.; Doke, Aniruddha K.; Garg, Pr 📂 Article 📅 2009 🏛 American Chemical Society 🌐 English ⚖ 460 KB

The synthesis and evaluation of N1-(4-(2

The synthesis and evaluation of N1-(4-(2-[18F]-fluoroethyl)phenyl)-N8-hydroxyoctanediamide ([18F]-FESAHA), A PET radiotracer designed for the delineation of histone deacetylase expression in cancer

✍ Brian M. Zeglis; NagaVaraKishore Pillarsetty; Vadim Divilov; Ronald A. Blasberg; 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 910 KB

Synthesis, in vitro and in vivo evaluati

Synthesis, in vitro and in vivo evaluation of [O-methyl-11C] 2-{4-[4-(3-methoxyphenyl)piperazin-1-yl]-butyl}-4-methyl-2H-[1,2,4]-triazine-3,5-dione: A novel agonist 5-HT1A receptor PET ligand

✍ Jaya Prabhakaran; Ramin V. Parsey; Vattoly J. Majo; Shu-Chi Hsiung; Matthew S. M 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 200 KB

Synthesis and in Vivo Evaluation of Fluo

Synthesis and in Vivo Evaluation of Fluorine-18 and Iodine-123 Labeled 2β-Carbo(2-fluoroethoxy)-3β-(4‘-(( Z )-2-iodoethenyl)phenyl)nortropane as a Candidate Serotonin Transporter Imaging Agent

✍ Plisson, Christophe; Stehouwer, Jeffrey S.; Voll, Ronald J.; Howell, Leonard; Vo 📂 Article 📅 2007 🏛 American Chemical Society 🌐 English ⚖ 219 KB

Synthesis and in vivo evaluation of [O-m

Synthesis and in vivo evaluation of [O-methyl-11C] 2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methyl- piperidin-4-yl)acetamide as an imaging probe for 5-HT2A receptors

✍ Jaya Prabhakaran; Ramin V. Parsey; Vattoly J. Majo; Ronald L. Van Heertum; J. Jo 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 224 KB 👁 1 views

## Abstract 2‐(4‐Methoxyphenyl)‐__N__‐(4‐methylbenzyl)‐__N__‐(1‐methylpiperidin‐4‐yl)acetamide (AC90179, **4**), a highly potent and selective competitive 5‐HT~2A~ antagonist, was labeled by [^11^C]‐methylation of the corresponding desmethyl analogue **5** with [^11^C]methyl triflate. The precursor