✦ LIBER ✦

Preparation and properties of a mouse monoclonal antibody (W14A) to human chorionic gonadotropin

✍ Scribed by F. Searle; C. S. Partridge; A. Kardana; A. J. Green; R. G. Buckley; R. H. J. Begent; G. A. Rawlins

Publisher: John Wiley and Sons
Year: 1984
Tongue: French
Weight: 570 KB
Volume: 33
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910330402

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✦ Synopsis

Abstract

A mouse monoclonal antibody, W14A, has been prepared which reacts with intact human chorionic gonadotropin and its beta‐subunit, showing less than 2% cross‐reactivity towards the alpha‐subunit and 0.5% cross‐reactivity towards the beta‐subunit of luteinizing hormone. The reagent is suitable for the radioimmunolocalization of choriocarcinoma and trophoblastic teratoma in humans. A preliminary radioimmunoassay has been developed.

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