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Preparation and in vivo evaluation of novel linkers for 211At labeling of proteins

โœ Scribed by Vladimir S. Talanov; Alexander T. Yordanov; Kayhan Garmestani; Diane E. Milenic; Hans C. Arora; Paul S. Plascjak; William C. Eckelman; Thomas A. Waldmann; Martin W. Brechbiel


Book ID
116798817
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
366 KB
Volume
31
Category
Article
ISSN
0969-8051

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The a-particle emitter '''At was covalently coupled to 1.8 pm aminated monodisperse polymer particles (MDPP) and used to irradiate the intraperitoneal cavity in mice with disseminated turnour cells. Specific activity has previously been shown to influence the therapeutic efficacy of a-particle emitt