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Preparation and evaluation of mannose receptor mediated macrophage targeting delivery system

โœ Scribed by Li Zhu; Li Chen; Qing-Ri Cao; Dawei Chen; JingHao Cui

Book ID
113694794
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
385 KB
Volume
152
Category
Article
ISSN
0168-3659

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A vaccine delivery system based on mannosylated chitosan microspheres (MCMs) was studied in vitro and in vivo. Bordetella bronchiseptica antigens containing dermonecrotoxin (BBD) were loaded in MCMs or chitosan microspheres (CMs). Fluorescence confocal microscopy indicated that BBD-loaded MCMs (BBDe