𝔖 Bobbio Scriptorium
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Preparation and evaluation of a series of α-hydroxy ethers from 9,10-epoxystearates

✍ Scribed by Bryan R. Moser; Sevim Z. Erhan


Book ID
102173565
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
284 KB
Volume
109
Category
Article
ISSN
1438-7697

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A new method for the stereoselective preparation of proximal b-hydroxy silyl enol ethers from a,bepoxyketones using silyllithium reagents has been developed. The reaction is believed to proceed via Brook rearrangement assisted by opening of the adjacent epoxide. A number of a,b-epoxyketones were rea