𝔖 Bobbio Scriptorium
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Preparation and applications of biofunctionalized, supported lipid bilayers and vesicles

✍ Scribed by Bengt Kasemo

Book ID
107574834
Publisher
Springer
Year
2005
Tongue
English
Weight
59 KB
Volume
1
Category
Article
ISSN
1551-1286

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## Abstract __We investigate the Ca^2+^‐triggered fusion of lipid vesicles site‐selectively tethered to a DNA‐modified supported lipid bilayer array, with the DNA strands designed such that hybridization occurs in a zipperlike fashion. Prior to the addition of Ca^2+^, which is observed to induce do

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Site-specific DNA-programmed single-vesicle fusion to a supported lipid bilayer is demonstrated by F. Hççk et al. on p. 1011. Cholesterol-modified DNA zippers are used to constitute a reduced model system of the SNARE-protein complex controlling synaptic vesicle fusion.