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Preparation and antiinflammatory properties of some 1-substituted 3-(5-tetrazolylmethyl)indoles and homologs

✍ Scribed by Juby, Peter F.; Hudyma, T. W.


Book ID
120323853
Publisher
American Chemical Society
Year
1969
Tongue
English
Weight
618 KB
Volume
12
Category
Article
ISSN
0022-2623

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Preparation of the 5-substituted azepino [3,4-b]indole core structure can be realised through a catalytic Heck reaction. The scope and limitations of this methodology are reported. The reactivity of di-tert-butyl 5ethoxycarbonylmethylene-1,3,4,5-tetrahydro-1-oxoazepino[3,4-b]indole-2,10-dicarboxylat