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Prenylated xanthones: antiproliferative effects and enhancement of the growth inhibitory action of 4-hydroxytamoxifen in estrogen receptor-positive breast cancer cell line

✍ Scribed by Ana Mafalda Paiva; Maria Emília Sousa; Ana Camões; Maria São José Nascimento; Madalena Maria Magalhães Pinto


Book ID
113015035
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
503 KB
Volume
21
Category
Article
ISSN
1054-2523

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## Abstract Although tamoxifen (TAM) is used for the front‐line treatment and prevention of estrogen receptor‐positive (ER+) breast tumors, nearly 40% of estrogen‐dependent breast tumors do not respond to TAM treatment. Moreover, the positive response is usually of short duration, and most tumors e