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Prenatal genotyping of ataxia-telangiectasia

✍ Scribed by RichardA. Gatti; KristinL. Peterson; Jessica Novak; Xiaoguan Chen; Lan Yang-Chen; Teresa Liang; Ethan Lange; Kenneth Lange


Book ID
119066190
Publisher
The Lancet
Year
1993
Tongue
English
Weight
160 KB
Volume
342
Category
Article
ISSN
0140-6736

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Ataxia telangiectasia (AT) is a severe autosomal recessive disease, rare but not infrequent in Italy. Owing to the seriousness of the disease, prenatal diagnosis has been attempted in the past by means of cytogenetic, biochemical, radio-biological and indirect molecular analyses. We performed the fi

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