Prenatal diagnosis of unusual hemoglobin
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Kim, Jong-Hwa ;Lebo, Roger V. ;Cai, Shi-Ping ;Su, Xia ;Chung, Jae-Hyun ;Mentzer,
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Article
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1994
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John Wiley and Sons
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English
⚖ 591 KB
While analyzing 280 hemoglobinopathy kindreds with prescribed molecular tests, 3 unusual mutations were observed that required additional characterization. In the first case, the hypervariable region flanking the a-globin genes generated an intermediate length 8.2 kb qc-globin gene fragment on a Sou