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Prenatal cocaine and morphine alter brain cyclin-dependent kinase 5 (Cdk5) activity in rat pups

โœ Scribed by Rama Bhat; Gopal Chari; Ravi Rao; David Wirtshafter


Book ID
113825226
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
125 KB
Volume
28
Category
Article
ISSN
0892-0362

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## Abstract Roscovitine, a cyclinโ€dependent kinase (Cdk) inhibitor, inhibited kinase activity and the axenic growth of __Dictyostelium discoideum__ at micromolar concentrations. Growth was almost fully rescued in 50โ€‰ยตM and โˆผ50% rescued in 100โ€‰ยตM roscovitineโ€treated cultures by the overโ€expression o