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Preliminary evidence for a pyridine nucleotide cycle inBordetella pertussis

โœ Scribed by W. L. McPheat

Book ID
104759654
Publisher
Springer Netherlands
Year
1984
Tongue
English
Weight
201 KB
Volume
50
Category
Article
ISSN
0003-6072

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โœฆ Synopsis

Preliminary evidence that Bordetella pertussis has a functional pyridine nucleotide cycle was the observation that [14C]-nicotinic acid was rapidly metabolized during its uptake by the bacteria to pyridine nucleotides and nicotinamide. Nicotinamide deamidase activity, necessary for the completion of the cycle by conversion of nicotinamide to nicotinic acid, was found in a soluble extract (20 000 X g supernatant) of B. pertussis cell lysates.

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