𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Prelamin A processing and heterochromatin dynamics in laminopathies

✍ Scribed by Nadir M. Maraldi; Elisabetta Mattioli; Giovanna Lattanzi; Marta Columbaro; Cristina Capanni; Daria Camozzi; Stefano Squarzoni; Francesco A. Manzoli

Book ID
113418931
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
246 KB
Volume
47
Category
Article
ISSN
0065-2571

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Effects of prelamin A processing inhibit
Effects of prelamin A processing inhibitors on the differentiation and activity of human osteoclasts
✍ Nicoletta Zini; Sofia Avnet; Sonia Ghisu; Nadir Mario Maraldi; Stefano Squarzoni 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 412 KB

## Abstract Osteoclast differentiation is a complex process involving cytoskeleton and nuclear reorganization. Osteoclasts regulate bone homeostasis and have a key role in bone degenerative processes. Osteolysis and osteoporosis characterize a subset of laminopathies, inherited disorders due to def

Pre-Lamin A processing is linked to hete
Pre-Lamin A processing is linked to heterochromatin organization
✍ Giovanna Lattanzi; Marta Columbaro; Elisabetta Mattioli; Vittoria Cenni; Daria C 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 283 KB

## Abstract Pre‐lamin A undergoes subsequent steps of post‐translational modification at its C‐terminus, including farnesylation, methylation, and cleavage by ZMPSTE24 metalloprotease. Here, we show that accumulation of different intermediates of pre‐lamin A processing in nuclei, induced by express