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Pre-Lamin A processing is linked to heterochromatin organization

✍ Scribed by Giovanna Lattanzi; Marta Columbaro; Elisabetta Mattioli; Vittoria Cenni; Daria Camozzi; Manfred Wehnert; Spartaco Santi; Massimo Riccio; Rosalba Del Coco; Nadir M. Maraldi; Stefano Squarzoni; Roland Foisner; Cristina Capanni

Book ID
102301468
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
283 KB
Volume
102
Category
Article
ISSN
0730-2312

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πŸ“œ SIMILAR VOLUMES

Pre-Lamin A processing is linked to hete
Pre-Lamin A processing is linked to heterochromatin organization
✍ Giovanna Lattanzi; Marta Columbaro; Elisabetta Mattioli; Vittoria Cenni; Daria C πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 283 KB

## Abstract Pre‐lamin A undergoes subsequent steps of post‐translational modification at its C‐terminus, including farnesylation, methylation, and cleavage by ZMPSTE24 metalloprotease. Here, we show that accumulation of different intermediates of pre‐lamin A processing in nuclei, induced by express