## Abstract ## BACKGROUND The impact of prenatal diagnosis on the live birth prevalence of Down syndrome (trisomy 21) has been described. This study examines the prevalence of Down syndrome before (1990β1993) and after inclusion of prenatally diagnosed cases (1994β1999) in a populationβbased regis
Pregnancy screening and prenatal diagnosis of fetal Down syndrome
β Scribed by Rose, Nancy C.
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 623 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1080-4013
No coin nor oath required. For personal study only.
β¦ Synopsis
This review discusses current methods for pregnancy screening and the prenatal diagnosis of fetal Down syndrome. These include maternal serum screening ultrasonographic evaluations, and standard prenatal diagnostic techniques. In addition t o noting the advantages and limitations of these methods, attention is directed to innovative prenatal diagnostic techniques that are not yet clini- cally available, such as the extraction of fetal cells from the maternal circulation and the preimplantation genetic diagnosis for fetal aneuploidies.
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