𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Preformulation studies of spironolactone: Effect of pH, two buffer species, ionic strength, and temperature on stability

✍ Scribed by Yashoda Pramar; V. D. Gupta


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
239 KB
Volume
80
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Effect of pH and ionic strength on the p
✍ Jason Rexroad; Robert K. Evans; C. Russell Middaugh πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 210 KB

The thermal stability of adenovirus type 5 (Ad5) was investigated over the pH range 3-8 employing a variety of biophysical techniques under conditions of low and high ionic strength. Analysis of the structural stability of Ad5 by dynamic light scattering, intrinsic and extrinsic fluorescence, and se

Evaluation of the physical stability of
✍ Kai Zheng; C. Russell Middaugh; Teruna J. Siahaan πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 472 KB

The development of protein drugs has been hampered by difficulties in formulating them due to their inherent chemical and physical stability, which could generate problems during the late stages of development. Thus, a basic understanding of the effect of structural features on the physicochemical s

Effect of temperature and pH on the toxi
✍ Paul Illmer; Wolfgang Mutschlechner πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 102 KB

## Abstract Two coryneform bacteria __Arthrobacter__ sp. PI/1–95 __(Arth1)__ and __Arthrobacter__ sp. PI/3‐95 __(Arth3)__ were isolated from forest soil characterized and investigated with respect to their reaction towards aluminium (Al). Sigmoid functions were used to describe dose‐response relati

Effect of pH and Ionic Strength on the H
✍ Folawiyo, Yetunde L; Apenten, Richard K Owusu πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 587 KB

The heat stability of rapeseed 12s globulin (cruciferin) was examined using 8-anilinonaphthalene-l-sulphonic acid (ANS) as a fluorescence probe. Heating cruciferin (0.06-0.3 mg ml-in 10 mM glycyl-glycyl piperizine buffer, pH 7.0, with 0.1-1.0 M NaCl) for 20 min increased its hydrophobicity as monito