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Preferential interactions of proteins with solvent components in aqueous amino acid solutions

โœ Scribed by Tsutomu Arakawa; Serge N. Timasheff


Book ID
115705638
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
721 KB
Volume
224
Category
Article
ISSN
0003-9861

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An equation is derived relating total and preferential interactions of solvent components with macromolecules in a three-component system. Application of this equation to literature data shows that binding of non-polar solvents to proteins parallels the unfolding of the latter. This observation is d