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Preferential inhibition of the synthesis of 45S ribosomal RNA precursor by N-acetoxyacetylaminofluorene in rat liver epithelial cultures

✍ Scribed by Lawrence A. Kaplan; I. Bernard Weinstein

Book ID
113135615
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
823 KB
Volume
12
Category
Article
ISSN
0009-2797

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## Abstract Aflatoxin is a potent hepatocarcinogen. Biochemically the short‐term action which seems to be the most important is an inhibition of nucleic acid synthesis. Injection of low doses (from 500 to 1,000 ΞΌg/kg) made it possible to modulate the different inhibitions induced by aflatoxin. The