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Alterations in the Processing of Rat-Liver Ribosomal RNA Caused by Cycloheximide Inhibition of Protein Synthesis

โœ Scribed by Bistra B. STOYANOVA; Asen A. HADJIOLOV


Book ID
115118361
Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
719 KB
Volume
96
Category
Article
ISSN
1432-1327

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Cycloheximide (Cyh), administered at a dose of 5 mg/kg body wt blocks protein synthesis in normal rat liver (NRL) and regenerating rat liver (RRL). The rate of synthesis of 45S pre-rRNA in RRL, studied after RNA labelling in vivo is activated 2.8 times. Pre-r RNA synthesis in RRL is more sensitive t