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Preferential expression and function of Toll-like receptor 3 in human astrocytes

✍ Scribed by Cinthia Farina; Markus Krumbholz; Thomas Giese; Gunther Hartmann; Francesca Aloisi; Edgar Meinl


Book ID
113729445
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
227 KB
Volume
159
Category
Article
ISSN
0165-5728

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## Abstract Toll‐like receptors (TLRs) are innate immunity receptors that are expressed on a wide range of cell types, including CNS glial cells. In general, TLR engagement by specific sets of microbial ligands triggers production of pro‐inflammatory factors and enhances antigen‐presenting cell fun