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The physiological regulation of toll-like receptor expression and function in humans

✍ Scribed by Graeme I. Lancaster; Qamar Khan; Pam Drysdale; Fiona Wallace; Asker E. Jeukendrup; Mark T. Drayson; Michael Gleeson

Book ID: 110113237
Publisher: Cambridge University Press
Year: 2005
Tongue: English
Weight: 254 KB
Volume: 563
Category: Article
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2004.081224

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## Abstract Toll‐like receptors comprise a family of evolutionary conserved pattern recognition receptors that act as a first defense line in the innate immune system. Upon stimulation with microbial ligands, they orchestrate the induction of a host defense response by activating different signalin