Preferential breakage of sensitive regions of human chromosomes
β Scribed by B. R. Reeves; Sylvia D. Lawler
- Book ID
- 104701686
- Publisher
- Springer
- Year
- 1970
- Tongue
- English
- Weight
- 402 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0340-6717
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Silver-stained cells from 49 parents with a history of several abortions were compared with cells from 35 parents with normal liveborn children. The modal and mean number of silver-stained NORs (Ag-NORs) observed on D- or G-group chromosomes was similar in both groups and between males and females.
The utility of a newly synthesized chemical variation of DAPI (4'-6-diamidino-2-phenyl-indole), D 287/170, for differential staining of constitutive heterochromatin in man is demonstrated. Direct staining of human chromosomes with D 287/170 results in brilliant fluorescence of the paracentromeric C-