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Predominant and stable T cell responses to regions of myelin basic protein can be detected in individual patients with multiple sclerosis

✍ Scribed by Marco Salvetti; Giovanni Ristori; Mauro D'Amato; Carla Buttinelli; Marika Falcone; Cesare Fieschi; Hartmut Wekerle; Carlo Pozzilli


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
935 KB
Volume
23
Category
Article
ISSN
0014-2980

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πŸ“œ SIMILAR VOLUMES


T cell response to myelin basic protein
✍ Roland Liblau; Elisabeth Tournier-Lasserve; Jacqueline Maciazek; GΓ©rad Dumas; Od πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 388 KB

T cell lines and clones specific for human myelin basic protein (BP) were selected from three multiple sclerosis (MS) patients and two healthy subjects and tested for their proliferative responses to a battery of synthetic peptides, 9 to 21 amino acid residues long. The combined amino acid sequence

Human T-cell response to myelin basic pr
✍ E. Tournier-Lasserve; G. A. Hashim; Dr. M. A. Bach πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 712 KB

In order to explore the T-cell repertoire to myelin basic protein (BP) of both multiple sclerosis (MS) patients and healthy subjects (HS), we raised BP reactive T-cell lines from blood mononuclear cells of eight MS patients and five HS. These lines were triggered in vitro by human BP. When analyzing