Predictors of response to lithium augmentation in tricyclic antidepressant-resistant depression
✍ Scribed by T. Bschor; B. Canata; B. Müller-Oerlinghausen; M. Bauer
- Book ID
- 114130870
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 59 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0165-0327
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The addition of lithium to the tricyclic antidepressant medication of 11 depressed patients resulted in an increase in the prolactin response to L-tryptophan after both 4 days and 4 weeks of lithium treatment. There was also a significant fall in Hamilton Depression scores. The results suggest that
## Abstract ## Objective Clinical trials suggest between 30–50% of depressed patients have an inadequate outcome to antidepressant pharmacotherapy. Among the approaches to improve outcome has been augmentation with antipsychotic medications. We aim to investigate the efficacy and tolerability of a