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Predictors of neuropathological severity in 100 patients with Huntington's disease

✍ Scribed by Adam Rosenblatt; Margaret H. Abbott; Lisa M. Gourley; Juan C. Troncoso; Russell L. Margolis; Jason Brandt; Christopher A. Ross

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
83 KB
Volume
54
Category
Article
ISSN
0364-5134

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πŸ“œ SIMILAR VOLUMES

Complex I Defect in muscle from patients
Complex I Defect in muscle from patients with Huntington's disease
✍ Dr JoaquΓ­n Arenas; Yolanda Campos; RenΓ© Ribacoba; Miguel A. MartΓ­n; Juan C. Rubi πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 439 KB πŸ‘ 1 views

We found a variable defect of complex I of the mitochondrial respiratory chain, ranging in severity from 25% to 63% of control values, in muscle of patients with Huntington's disease (HD). The most severe defect was observed in the patient with the greatest expansion of CAG triplets. Muscle morpholo