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Higher sedentary energy expenditure in patients with Huntington's disease

✍ Scribed by Richard E. Pratley; Arline D. Salbe; Eric Ravussin; John N. Caviness


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
136 KB
Volume
47
Category
Article
ISSN
0364-5134

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Complex I Defect in muscle from patients
✍ Dr JoaquΓ­n Arenas; Yolanda Campos; RenΓ© Ribacoba; Miguel A. MartΓ­n; Juan C. Rubi πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 439 KB πŸ‘ 1 views

We found a variable defect of complex I of the mitochondrial respiratory chain, ranging in severity from 25% to 63% of control values, in muscle of patients with Huntington's disease (HD). The most severe defect was observed in the patient with the greatest expansion of CAG triplets. Muscle morpholo