Complex I Defect in muscle from patients
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Dr JoaquΓn Arenas; Yolanda Campos; RenΓ© Ribacoba; Miguel A. MartΓn; Juan C. Rubi
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Article
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1998
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John Wiley and Sons
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English
β 439 KB
π 1 views
We found a variable defect of complex I of the mitochondrial respiratory chain, ranging in severity from 25% to 63% of control values, in muscle of patients with Huntington's disease (HD). The most severe defect was observed in the patient with the greatest expansion of CAG triplets. Muscle morpholo